Off-label use of approved drugs
نویسندگان
چکیده
منابع مشابه
Off-label use of approved drugs: therapeutic opportunity and challenges.
In this issue of the JASN, Booth et al. (1) report a well-designed study using TNFblockade with infliximab (Remicade) to treat ANCA-associated systemic vasculitis. The use of infliximab, already approved by the US Food and Drug Administration (FDA) for treatment of inflammatory bowel disease, raises the general question of off-label uses of approved drugs. Clearly, off-label use of drugs by ind...
متن کاملOff-label use of drugs in children.
The passage of the Best Pharmaceuticals for Children Act and the Pediatric Research Equity Act has collectively resulted in an improvement in rational prescribing for children, including more than 500 labeling changes. However, off-label drug use remains an important public health issue for infants, children, and adolescents, because an overwhelming number of drugs still have no information in ...
متن کاملUse of off-label and non-approved drugs and devices in plastic surgery.
Our ultimate goal as plastic surgeons is to provide the best possible result for our patients with the minimum amount of morbidity. In our rapidly expanding technological world, various drugs and devices have been developed in the hope of continual improvement of outcomes and, therefore, patient satisfaction. According to a joint advisory issued by the American Society of Plastic Surgeons and t...
متن کاملChinese regulation of off-label use of drugs.
China has significant gaps and weaknesses in its regulatory oversight of the off-label use of drugs. As in the United States, the off-label prescribing of drugs is not prohibited in China if there is a sound scientific basis. Physicians are allowed to prescribe off-label drugs based on their medical judgment if they follow certain requirements. There is some constraint on the right to prescribe...
متن کاملOff-label Use of Drugs in the Neuroendovascular Suite
SUMMARY: The off-label use of drugs and devices in neuroendovascular procedures is common. Neurointerventionalists should be well aware of the level of evidence available in support of the off-label use of drugs and devices in their practice and some of the potential adverse events associated with them. These uses are categorized as I or II if they have been evaluated as primary or ancillary in...
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ژورنال
عنوان ژورنال: Nature Reviews Clinical Oncology
سال: 2009
ISSN: 1759-4774,1759-4782
DOI: 10.1038/nrclinonc.2009.41